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Martin Moune Selected Research

Ethionamide (Trecator-SC)

1/2022The small-molecule SMARt751 reverses Mycobacterium tuberculosis resistance to ethionamide in acute and chronic mouse models of tuberculosis.
1/2020Fragment-Based Optimized EthR Inhibitors with in Vivo Ethionamide Boosting Activity.
1/2019A comprehensive analysis of the protein-ligand interactions in crystal structures of Mycobacterium tuberculosis EthR.
3/2017Reversion of antibiotic resistance in Mycobacterium tuberculosis by spiroisoxazoline SMARt-420.

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Martin Moune Research Topics

Disease

3Tuberculosis (Tuberculoses)
01/2022 - 01/2019
2Infections
01/2020 - 03/2017

Drug/Important Bio-Agent (IBA)

4Ethionamide (Trecator-SC)FDA Link
01/2022 - 03/2017
1Mixed Function Oxygenases (Monooxygenases)IBA
01/2022
1ProdrugsIBA
01/2022
1Anti-Bacterial Agents (Antibiotics)IBA
01/2022
1OxadiazolesIBA
01/2020
1Proteins (Proteins, Gene)FDA Link
01/2019
1SMARt-420IBA
03/2017